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Table 3 Comparison of experimental data and predicted values of accumulation rates of various metabolites at different time points

From: Analysis of optimal phenotypic space using elementary modes as applied to Corynebacterium glutamicum

Accumulation rate (mM/h)

NH3

O2

CO2

Time (h)

Expt.

Predicted

Expt

Predicted

Expt

Predicted

11.5

-67.72

-66.88

-230.68

-237.1

251.79

255.2

13.5

-96.89

-97.67

-177.4

-172.48

218.6

212.74

15.8

-78.24

-76.02

-221.4

-236.77

257.89

270.8

  1. Glucose, lysine, trehalose and Biomass were the decision variables to the linear programming optimizer with the objective function of maximization of carbon dioxide. Values predicted were for the uptake rates of ammonia, oxygen and accumulation rate of carbon dioxide. It was observed that the choice of decision variables of accumulation rates and objective function yielded the same prediction of extracellular accumulation rates.
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BMC Bioinformatics

ISSN: 1471-2105

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