Figure 2From: inGeno – an integrated genome and ortholog viewer for improved genome to genome comparisonsGenome comparison between closely related strains. The comparison between two closely related E. coli K-12 strains (W3110 and MG1655) indicates these are only slightly different, except for a highlighted large inversion. The upper genome is W3110 [24], whereas the lower genome is MG1655 [23-25]. Using inGeno, a couple of strain-specific genes are readily seen, such as TnaB (annotated as low affinity tryptophan permease; b3709 in figure) and other genes (DcuC: b0621, GatA: b2094, RcsC: b2218), which lead to different metabolic capabilities, e.g., the utilization of tryptophan as carbon source may be impaired in W3110.Back to article page