Figure 4From: The accuracy of several multiple sequence alignment programs for proteinsComparison of alignment accuracy and increasing sequence length, at high indel frequency values. Selected examples obtained with different tree topologies. ProbCons and Mafft L-INS-i took turns as top performers. A middle group of programs is revealed by this comparison, comprising Mafft FFT-NS-2, T-Coffee, Muscle and Kalign. The smallest accuracies were shown by Dialign2.2, Dialign-T and POA, and Clustal W at large sequence sizes. Clustal W curves presented a steep decline in accuracy as the sequence length was increased.Back to article page