Figure 8
From: Using the nucleotide substitution rate matrix to detect horizontal gene transfer
Improved detection of simulated HGT events using our new statistics. The histograms show the discrimination using GC content, statistic 45 (left), and ratio of first two singular values in three-way comparisons, statistic 41 (right). The new statistic is considerably better at classifying the HGT (red) and non-HGT (blue) phylogenies, as shown by the greater separation between the two histograms. Statistic 41 gives an optimal classifier with 1.5% false positives and 5% false negatives, a threefold improvement in discrimination over statistic 45. Data shown are from 1000 balanced 16-sequence trees of each type, with an average divergence of 10% between sister taxa.