Skip to main content
Figure 2 | BMC Bioinformatics

Figure 2

From: RiboSubstrates: a web application addressing the cleavage specificities of ribozymes in designated genomes

Figure 2

Design of RiboSubstrates with the parameters for the SOFA-HDV ribozyme. (A) Secondary structure and nucleotide sequence of the SOFA-HDV ribozyme targeting an mRNA. The P1 stem of the ribozyme and the biosensor (BS) of the SOFA module are identified. The letter N indicates the presence of an A, C, G or T residue. The arrow indicates the cleavage site. (B) The RiboSubstrates input with the signature to be searched for the SOFA-HDV-Rz targeting the HCV virus (SOFA-HDV-Rz-135) and the substrate display table. Mismatched nucleotides and Wobble base pairs are identified in red and blue, respectively. (C) The more detailed tables for both the mRNA encoding the HCV genome 1b and the predicted Homo sapiens LOC440096, respectively.

Back to article page

BMC Bioinformatics

ISSN: 1471-2105

Contact us