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Table 7 The biological meaning of the feasible t-invariants.

From: Application of Petri net based analysis techniques to signal transduction pathways

No.

Biological meaning

1.

Dissociation and reassociation of the G protein subunits

2.

Endocytosis of the activated receptor

7.

Changed gene transcription, cell cycle arrest, de-/phosphorylation Kss1

8.

Changed gene transcription, Far1 transport out of the nucleus, de-/phosphorylation Kss1

9.

Changed gene transcription, cell cycle arrest, repression of Ste12 through inactive Fus3

10.

Changed gene transcription, Far1 transport out of the nucleus, repression of Ste12 through inactive Fus3

11.

Signalling via the cascade, feedback degradation of Ste11

12.

Signalling via the cascade feedback degradation of Ste7

13.

Signalling via the cascade, repression of Ste12 through inactive Kss1

14.

Signalling via the cascade, phosphorylation and dephosphorylation of Kss1

  1. The feasible t-invariants of Table 6 with their biological meaning. All of them involve the receptor activation, which is not explicitly mentioned, here.