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Table 2 Optimal parameters for the HIV proteinase inhibition problem

From: Novel metaheuristic for parameter estimation in nonlinear dynamic biological systems

Results SSm
Parameter Parameter value (J = 0.0199) Parameter value (J = 0.0203)
k 3 6.235 ± 3.2546 5.656 ± 1.953
k 42 8772 ± 46120 688.4 ± 3436
k 22 473.0 ± 624.6 120.6 ± 508.1
k 52 0.09726 ± 0.1288 4.615 ± 583.4
k 6 0.01417 ± 0.01032 3.531 ± 455.4
S0 (exp 1) 24.63 ± 0.07817 24.69 ± 0.08049
S0 (exp 2) 23.32 ± 1.349 23.43 ± 0.1541
S0 (exp 3) 26.93 ± 1.222 27.11 ± 0.1672
S0 (exp 4) 13.34 ± 1.822 17.07 ± 1.986
S0 (exp 5) 12.50 ± 1.812 14.49 ± 1.757
E0 (exp 1) 0.005516 ± 0.001968 0.005397 ± 0.0009091
E0 (exp 2) 0.005321 ± 0.001309 0.005199 ± 0.0005520
E0 (exp 3) 0.006000 ± 0.001111 0.006000 ± 0.0005489
E0 (exp 4) 0.004391 ± 0.00008686 0.004264 ± 0.00005821
E0 (exp 5) 0.003981 ± 0.00008844 0.003973 ± 0.00005648
offset (exp 1) -0.004339 ± 0.001788 -0.005611 ± 0.001836
offset (exp 2) -0.001577 ± 0.002966 -0.004247 ± 0.003432
offset (exp 3) -0.01117 ± 0.002734 -0.01522 ± 0.003865
offset (exp 4) -0.001661 ± 0.001881 -0.009649 ± 0.003277
offset (exp 5) 0.007133 ± 0.001764 0.001329 ± 0.003178