TY - JOUR AU - Shida, Kazuhito PY - 2006 DA - 2006/11/04 TI - GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima JO - BMC Bioinformatics SP - 486 VL - 7 IS - 1 AB - Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sampling based technique for TFBS discovery is attempted through an approach that is widely known, but which has never been investigated before: reduction of the effect of local optima. SN - 1471-2105 UR - https://doi.org/10.1186/1471-2105-7-486 DO - 10.1186/1471-2105-7-486 ID - Shida2006 ER -