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Table 2 External databases successfully imported into cPath.

From: cPath: open source software for collecting, storing, and querying biological pathways

Database Name

Database Type

URL

Release Date Tested

Data Format used for cPath Import

Database Stats

Cancer Cell Map

Signaling Pathways

http://cancer.cellmap.org

April, 2006

BioPAX, Level 2

Pathways: 10

Interactions: 2,104

Physical Entities: 899

Database of Interacting Proteins (DIP) [54, 55]

Protein-Protein Interactions

http://dip.doe-mbi.ucla.edu/

April, 2006

PSI-MI, Level 1

Interactions: 54,511

Physical Entities: 19,003

Ecocyc [56]

Metabolic and Signaling Pathways

http://ecocyc.org/ Registration required to download data

March, 2006

BioPAX, Level 1

Pathways: 224

Interactions: 4,644

Physical Entities: 3,511

Human Protein Reference Database (HPRD) [57]

Protein-Protein Interactions

http://hprd.org/ Registration required to download data

Sept, 2005

PSI-MI, Level 1

Interactions: 4,450

Physical Entities: 12,226

IntAct [46]

Protein-Protein Interactions

http://www.ebi.ac.uk/intact

May, 2006

PSI-MI, Level 1

Interactions: 67,816

Physical Entities: 28,006

KEGG [58, 59]

Metabolic Pathways

ftp://ftp.genome.jp/pub/db/community/biopax/

July, 2006

BioPAX, Level 2

Human Data Only Pathways: 108

Interactions: 3,285

Physical Entities: 2,018

Molecular Interaction Database (MINT) [45]

Protein-Protein Interactions

http://mint.bio.uniroma2.it/mint/

May, 2005

PSI-MI, Level 1

Interactions: 44,904

Physical Entities: 16,325

Reactome [47]

Metabolic and Signaling Pathways

http://reactome.org/

May, 2006

BioPAX, Level 2

Human Data Only Pathways: 775

Interactions: 2,962

Physical Entities: 3,197