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Table 3 Results on HLA-DRB1*0101 and HLA-DRB1*0301

From: Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores

Allele Method Acc. AROC AROC50 MCC AOVER-ROC
HLA-DRB1*0101 SKM (β = 0.04) 0.886 0.912 0.804 0.643 0.088
  SKM (β = 0.085) 0.901 0.904 0.778 0.690 0.096
  LP_top2   0.779    0.221
  TEPITOPE   0.842    0.158
HLA-DRB1*0301 SKM (β = 0.06) 0.763 0.823 0.580 0.531 0.177
  SKM (β = 0.08) 0.757 0.827 0.575 0.525 0.173
  LP_top2   0.721    0.279
  TEPITOPE   0.585    0.415
  1. Results of 5-fold cross-validation with best results shown in bold. Results from LP_top2 and TEPITOPE are taken from [21]. Measurements are same as previously reported, except for AOVER-ROC, which is the area over the ROC curve. AROC = 1.00 is perfect classification, so AOVER-ROC, 1- AROC, can be seen as an error measure.