Figure 2

Local gene correlations example. Example of Local gene correlations. The plot to the left shows the expression profiles of 7 genes during the cell cycle (data from Cho et al. [29]). Three different time windows are marked by vertical lines. The Venn diagram to the right assigns the genes to clusters of co-expressed genes (correlation coefficient > 0.7) for the respective time windows. Although there are some visible correlations in all three time windows, these similarities cannot be well described by means of global correlation. Introducing analysis of local similarity allows for a better gene clustering, as shown in the Venn diagram.