CoXpress: differential co-expression in gene expression data

BMC Bioinformatics

Table 5 Differentially co-expressed groups from the ALL subtype dataset

group	N	t1	t2	pr.g2	mean.corr1	mean.corr2	robustness
47	16	59.8611	2.453073	0.0684	0.66915	0.05863	805
31	10	29.20261	2.194293	0.0677	0.64726	0.07787	861
89	13	42.1617	1.934779	0.0904	0.63834	0.04420	885
41	11	30.19613	1.122452	0.2115	0.63042	0.05146	986
25	12	34.18317	2.531833	0.0503	0.62832	0.10027	686
9	14	30.35473	2.324388	0.0655	0.59705	0.06109	829
71	13	33.96871	2.236447	0.0658	0.58783	0.05880	855
15	19	45.6475	1.865767	0.1373	0.58500	0.03853	1000
103	10	29.54434	-1.24949	0.9613	0.58393	-0.03758	1000
19	20	45.45846	1.509674	0.2093	0.5810	0.02446	1000
11	16	43.62891	1.402566	0.1964	0.57995	0.02908	1000
114	12	32.84917	1.192507	0.205	0.57624	0.03668	995
32	13	34.2227	1.097651	0.2275	0.57004	0.03208	982

Differentially co-expressed groups from the ALL subtype dataset of Yeoh et al [23]. Group is the group number, N is the group size, t1 and t2 are the observed t-statistics in the BCR-ABL and T-ALL1 subsets, pr.g1 and pr.g2 are the probability of randomness statistics for the BCR-ABL and T-ALL1 subsets, mean.corr1 and mean.corr2 are the mean pairwise correlation coefficients for the genes in the BCR-ABL and T-ALL1 subsets and robustness is the number of times that the group was differentially co-expressed in 1000 randomly resampled data sets using only 75% of the observations in each leukaemia subtype. Groups are ordered by mean.corr1. The table has been filtered such that pr.g1 ≤ 0.05, pr.g2 ≥ 0.05 and N ≥ 10.

ISSN: 1471-2105