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Table 6 Performance on independent datasets.

From: An accurate and interpretable model for siRNA efficacy prediction

Dataset Sparse Spectral Composite BIOPREDsi
Harborth (44) 0.43 0.49 0.48 0.45
Reynolds (240) 0.54 0.49 0.55 0.55
Vickers (76) 0.58 0.54 0.49 0.57
Shabalina (653) 0.48 0.45 0.48 -
  1. This table shows the performance of the LASSO model with different features (sparse-19, spectrum-19, composite-19/19) on four independent datasets, as well as the performance of the BIOPREDsi algorithm on the the first three datasets (from Huesken et al. [33]). The performance is measured as the Pearson correlation coefficient between predicted and true efficacy).