Figure 4

Chr Y Analysis and Sensitivity to Gender. A) The SVD decomposition of Chr.Y alone determined a uniform pattern spanning the entire chromosome. B) Illustration of the corresponding case loadings indicating the amount of expression of the chromosomal pattern expressed by each case. In this convention, positive values indicate loss of expression. Dark bars indicate male cases while white bars indicate female cases. There is an obvious and clear separation between arrays due to gender although a loss of Y expression is detected in tumour tissue for case O3.