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Figure 5 | BMC Bioinformatics

Figure 5

From: PDB-UF: database of predicted enzymatic functions for unannotated protein structures from structural genomics

Figure 5

FSSP (on the left) and 3D-Fun (on the right) Z-score of the most similar protein with the same enzyme function at the all EC level versus Z-score of the most similar protein with different enzyme function at any EC level. Calculation was conducted for 3,135 sequentially non-redundant structures of known function. Corresponding histograms are shown below the charts. If FSSP Z-score = 23 and 3D-Fun Z-score = 9 were used as a cutoff value we would obtain sensitivity of 55% and 60% with specificity at 53% and 55%, respectively.

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