Figure 7

Distribution of consistent (blue lines) and inconsistent (red lines) predictions of an enzyme function conducted using 3D-Hit (left charts) and 3D-Fun (right charts) algorithms. The assignments were performed at the 1^st (upper charts), 2^nd (middle charts), and 3^rd EC level (lower charts) for 499 proteins of unknown function from the structural genomics centers. Marked cutoff values (3D-Hit = 89 and 3D-Fun = 3.1) corresponds to a 50:50 probability of assigning a consistent EC number.