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Table 2 Determination of position-dependent nucleotide preferences and avoidances by t-test analysis.

From: Computational models with thermodynamic and composition features improve siRNA design

Nucleotide and position t-test p-value Average activity if this nucleotide is:
Preferred Avoided   present absent
U1   5.6e-13 29.78 47.49
  C1 3e-07 53.04 38.64
C19   2.9e-06 34.19 45.95
  A19 2.1e-05 51.80 39.84
  G1 8.3e-05 51.59 39.94
U13   0.00058 36.39 45.03
U2   0.00108 37.17 44.75
  G2 0.00155 49.75 40.49
  G7 0.00209 48.71 40.42
A7   0.00253 36.15 44.11
U7   0.00296 37.43 44.65
  G13 0.00433 47.84 40.78
A1   0.00523 37.31 44.04
  G6 0.00557 48.24 40.69
A10   0.00573 36.61 43.96
U14   0.00633 37.75 44.27
C17   0.00768 37.49 44.04
  C7 0.00854 47.67 40.79
A14   0.00972 37.36 43.83
  A17 0.01011 47.54 40.73
  A5 0.0104 47.31 40.85
  G14 0.01121 47.59 40.88
U3   0.01599 38.01 44.03
C18   0.01653 38.35 44.03
  C14 0.02243 46.65 40.87
  A11 0.02601 47.00 41.20
U5   0.02657 39.01 44.06
  G16 0.02902 46.56 41.09
  U19 0.02982 46.47 41.09