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Table 4 The value of R2 (50-split average) for neural networks after a given parameter is removed. The standard deviation of the 50-split average is also shown.

From: Computational models with thermodynamic and composition features improve siRNA design

Neural Networks configuration

R

R 2

std. dev.

18 × 1

0.5222

0.2727

0.0073

18 × 2 × 1

0.5310

0.2820

0.0066

18 × 3 × 1

0.5310

0.2820

0.0062

18 × 4 × 1

0.5306

0.2815

0.0065

18 × 6 × 1

0.5302

0.2811

0.0061

18 × 8 × 1

0.5296

0.2805

0.0064

18 × 2 × 2 × 1

0.5322

0.2832

0.0058

18 × 3 × 2 × 1

0.5324

0.2834

0.0061

18 × 3 × 3 × 1

0.5322

0.2832

0.0059

18 × 4 × 3 × 1

0.5321

0.2831

0.0063

18 × 6 × 2 × 1

0.5315

0.2825

0.0058

18 × 2 × 2 × 2 × 1

0.4041

0.1633

0.0704