Figure 7From: The PowerAtlas: a power and sample size atlas for microarray experimental design and researchIdealized representation of the distribution of p-values under the null hypothesis (no difference in gene expression between the two groups) for a valid test. The dotted Blue line is the expected distribution of p-values if the treatment has no effect and the solid Green line is the mixed-model [23] fit of the p-value constrained to be monotonically non-decreasing.Back to article page