A sample calculation of the average persistence for a single node. The average persistence is calculated by comparing the persistence at each node in the tree given in Figure 4. Each assignment of each mutant (4 are shown here) to a pattern is binarized as described in the text, then the average persistence for a node is calculated by checking on the number of times the mutant assigned to the pattern occurs in the connected nodes. The mutant can occur in any branch below the node of interest to be considered as present. If it occurs in multiple child nodes at a single level, that is still treated as a single occurrence for that level. The average for a dimension is then the average of the persistence of all nodes at that level.