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Figure 8 | BMC Bioinformatics

Figure 8

From: The Cluster Variation Method for Efficient Linkage Analysis on Extended Pedigrees

Figure 8

Scaling of CVM computation time with number of markers. Scaling of CVM computation time with the number of marker loci is indicated by the crosses. Scaling of computation time is approximately linear. All individuals have marker information, the number of alleles is 2. The red curve represents computation time of Vitesse. Vitesse cannot handle more than 10 markers as memory requirements exceed system memory of 1 GB. For the problem of 32 markers, MCMC estimates take several hours to reach convergence.

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