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Table 3 The top 10 drugs by PCR performance improvement. Each row contains: a Drug ID; the NSC number of the drug; # Cells: the number of available cells; R1, the correlation coefficient before noise reduction; R2, the correlation coefficient after noise reduction; p(R1), the p-value (by one sample t-test) for R1; and p(R2), the p-value for R2.

From: Network-based de-noising improves prediction from microarray data

Top N Drug ID # Arrays R1 R2 p(R1) p(R2) P(R1)/P(R2)
1 642049 49 0.42 0.71 2.71E-03 8.41E-09 3.22E+05
2 644945 59 0.51 0.69 3.85E-05 1.38E-09 2.79E+04
3 691277 57 0.42 0.65 1.18E-03 5.75E-08 2.05E+04
4 645803 60 0.53 0.68 1.39E-05 2.83E-09 4.91E+03
5 32946 60 0.37 0.59 3.51E-03 8.01E-07 4.38E+03
6 628672 59 0.59 0.71 9.04E-07 2.06E-10 4.39E+03
7 642710 60 0.57 0.7 1.55E-06 4.00E-10 3.87E+03
8 665128 57 0.58 0.69 2.34E-06 2.16E-09 1.08E+03
9 694265 60 0.49 0.63 6.35E-05 6.40E-08 9.92E+02
10 668334 60 0.62 0.72 9.44E-08 1.07E-10 8.79E+02