Table 3 The top 10 drugs by PCR performance improvement. Each row contains: a Drug ID; the NSC number of the drug; # Cells: the number of available cells; R1, the correlation coefficient before noise reduction; R2, the correlation coefficient after noise reduction; p(R1), the p-value (by one sample t-test) for R1; and p(R2), the p-value for R2.
From: Network-based de-noising improves prediction from microarray data
Top N | Drug ID | # Arrays | R1 | R2 | p(R1) | p(R2) | P(R1)/P(R2) |
|---|---|---|---|---|---|---|---|
1 | 642049 | 49 | 0.42 | 0.71 | 2.71E-03 | 8.41E-09 | 3.22E+05 |
2 | 644945 | 59 | 0.51 | 0.69 | 3.85E-05 | 1.38E-09 | 2.79E+04 |
3 | 691277 | 57 | 0.42 | 0.65 | 1.18E-03 | 5.75E-08 | 2.05E+04 |
4 | 645803 | 60 | 0.53 | 0.68 | 1.39E-05 | 2.83E-09 | 4.91E+03 |
5 | 32946 | 60 | 0.37 | 0.59 | 3.51E-03 | 8.01E-07 | 4.38E+03 |
6 | 628672 | 59 | 0.59 | 0.71 | 9.04E-07 | 2.06E-10 | 4.39E+03 |
7 | 642710 | 60 | 0.57 | 0.7 | 1.55E-06 | 4.00E-10 | 3.87E+03 |
8 | 665128 | 57 | 0.58 | 0.69 | 2.34E-06 | 2.16E-09 | 1.08E+03 |
9 | 694265 | 60 | 0.49 | 0.63 | 6.35E-05 | 6.40E-08 | 9.92E+02 |
10 | 668334 | 60 | 0.62 | 0.72 | 9.44E-08 | 1.07E-10 | 8.79E+02 |