Figure 8
From: Nanopore Detector based analysis of single-molecule conformational kinetics and binding interactions
In preliminary nanopore studies the wild-type 3' end sequence (-C-A-T-G-3') was found to be similar to (-C-A-A-A-3'), which motivated the present study of a group of DNA hairpins consisting of all adenosines on the 3' side of the molecule, except for one cytosine-adenosine step. Contrary to the differences (seemingly) indicated by nature, the calculated ΔG° of hairpin formation (using MFold [54]) is the same for the set of molecules described, with one CA step (the CA set).