Figure 2

GOFFA interface and Tree Window – The GOFFA interface contains three panels: the left panel (labeled 1) is for queries, the center panel (labeled 2) for tabular and/or graphical displays of and for interaction with the GO information, and the right panel (labeled 3) lists the individual genes associated with the GO information presented in the center panel. The displayed Tree Window in the center panel is the default view of GOFFA, which enables the hierarchical display of the GO terms in a outline-like tree format; p- and E-values as well as the number of genes are also displayed for each GO term. E-values >1 are shown in green and those <1 in red, respectively denoting greater or lesser prevalence, respectively, of the GO term in the inputted gene list rather than in the overall experimental platform. The user can query the tree by GO term, gene name/symbol, p-value, E-value and in combination with functions below the view. The query-match GO terms are highlighted as blue.