Figure 4

GO Path – GO Path sorts, by descending statistical significance based on an inverse Chi-Squared test, the GOFFA Tree Paths (i.e., linked GO terms) and graphically displays them from high to low at each hierarchical level. GO Path plots the top ten paths with solid circles representing the GO terms on the path. The X-axis has the hierarchical level to which the GO term belongs and the Y-axis (log p) indicates the statistical significance of the term. A color key for the top 10 paths (as determined by equation 2) is located beneath the plot. Clicking either a circle in a path in the plot or its corresponding color key launches a Tree View (Figure 2) with the selected path highlighted in blue. Other features are also available from a popup menu obtained by right clicking the plot, including zoom in/out, export figure, etc.