Comparison of particle simulation and ODE results. The average of [P] plotted with time (sec) for Monte Carlo (particle) simulations (open symbols) and the corresponding rate equations (line curves). The activation energies and their corresponding kinetic parameters are listed in Table 2: (a) and (c) in Table 2 for (A), while (b) and (d) in Table 2 for (B). The total concentration of E is [E]0 = 0.1 μM. The initial distribution is random with equal probability for all the sites in the 3D space, with use of 16 samples.