Table 3 Residues in the binding pocket of NS3 of JEV and DEN-2. Active site residues are underlined and variations are shown in bold.
From: Curation of viral genomes: challenges, applications and the way forward
Binding pocket | JEV | DEN2 |
|---|---|---|
S2 | H51 | H51 |
| Â | D75 | D75 |
| Â | G151 | G151 |
| Â | N152 | N152 |
| Â | G153 | G153 |
S1 | L115 | V115 |
| Â | S131 | P131 |
| Â | S135 | S135 |
| Â | G136 | G136 |
| Â | Y150 | Y150 |
| Â | S163 | S163 |
S1' | Q35 | Q35 |
| Â | I36 | A36 |
| Â | H51 | H51 |
| Â | V52 | T52 |
| Â | S135 | S135 |
S2' | Q35 | Q35 |
| Â | I36 | A36 |
| Â | P132 | R132 |
| Â | G133 | G133 |
Hydrophobic cluster | L115 | V115 |
| Â | F116 | F116 |
| Â | V126 | V126 |
| Â | A160 | S160 |
| Â | Y161 | Y161 |