Figure 1
From: SVM-based prediction of caspase substrate cleavage sites
Different subsequence segments for SVM training and testing. For human Mcl-1 [Swiss-Prot:Q07820], a sequence window of 24 amino acids in length centred on the tetrapeptide cleavage site, TSTD (underlined) is shown. Amino acids to the left of the scissile bond (shown by the inverted triangle) are labelled from P1 (D) to P14 (L). Amino acids to the right of the scissile bond are labelled from P1' (G) to P10' (A). Curly brackets indicate the subsequence segments extracted for SVM implementation. The sequences spanning P4 to P1 (TSTD), P4 to P2' (TSTDGS) and P14 to P10' (LELVGEGSNNTSTDGSLPSTPPPA) are labelled as P4P1, P4P2' and P14P10' respectively.