Figure 2From: Prediction of desmoglein-3 peptides reveals multiple shared T-cell epitopes in HLA DR4- and DR6- associated Pemphigus vulgarisPredicted DQB1*0503-specific T-cell epitope repertoire within Dsg3. Location of predicted DQB1*0503-specific T-cell epitopes along the Dsg3 glycoprotein – extracellular domain (colored yellow; Dsg3 50–615), transmembrane region (colored green; Dsg3 616–640), and intracellular domain (colored pink; Dsg3 641–999). The red line indicates decision threshold -26.64 kJ/mol for high-affinity binders (SP = 0.80, SE = 0.65).Back to article page