Table 2 Predicted binding affinities of Dsg3 peptide sequences to DRB1*0402.
Rank | Peptide | Sequence | Predicted BE (kJ/mol) | References |
|---|---|---|---|---|
1 | Dsg3 342–358 | SVKLSIAVKNKAEFHQS | -31.46 | Veldman et al. (2004) |
2# | Dsg3 342–356 | SVKLSIAVKNKAEFH | -30.88 | Moesta et al. (2002) |
3 | Dsg3 205–221 | GTPMFLLSRNTGEVRTL | -30.44 | Veldman et al. (2004) |
4* # | Dsg3 846–860 | LDSLGPKFKKLAEIS | -30.17 | Moesta et al. (2002) |
5 | Dsg3 380–396 | GIAFRPASKTFTVQKGI | -29.97 | Riechers et al. (1999) |
6@ | Dsg3 67–81 | RNPIAKITSDYQATQ | -29.94 | Moesta et al. (2002) |
7 | Dsg3 786–800 | MNFLDSYFSQKAFAC | -29.78 | Moesta et al. (2002) |
8 | Dsg3 190–204 | LNSKIAFKIVSQEPA | -29.74 | Wucherpfennig et al. (1995) |
9 | Dsg3 189–205 | HLNSKIAFKIVSQEPAG | -29.24 | Veldman et al. (2004) |
10* | Dsg3 512–526 | SARTLNNRYTGPYTF | -29.21 | Wucherpfennig et al. (1995) |
11 | Dsg3 78–94 | QATQKITYRISGVGIDQ | -28.37 | Veldman et al. (2004) |
12* | Dsg3 78–93 | QATQKITYRISGVGID | -28.30 | Wucherpfennig et al. (1995) |
13 | Dsg3 191–205 | NSKIAFKIVSQEPAG | -28.16 | Moesta et al. (2002) |
14 | Dsg3 206–220 | TPMFLLSRNTGEVRT | -28.02 | Wucherpfennig et al. (1995) |
15 | Dsg3 210–226 | LLSRNTGEVRTLTNSL | -27.98 | Veldman et al. (2004) |
16 | Dsg3 251–265 | CECNIKVKDVNDNFP | -27.88 | Wucherpfennig et al. (1995) |
17 | Dsg3 250–266 | QCECNIKVKDVNDNFPM | -27.68 | Veldman et al. (2004) |
18 | Dsg3 483–499 | VRVPDFNDNCPTAVLEK | -27.48 | Veldman et al. (2004) |
19* @ | Dsg3 96–110 | PFGIFVVDKNTGDIN | -27.47 | Moesta et al. (2002) |
20 | Dsg3 762–776 | QSGTMRTRHSTGGTN | -27.28 | Wucherpfennig et al. (1995) |
21 | Dsg3 161–177 | IFMGEIEENSASNSLVM | -27.09 | Hertl et al. (1998) |
22 | Dsg3 96–112 | PFGIFVVDKNTGDINIT | -27.09 | Veldman et al. (2004) |
23@ | Dsg3 963–977 | ERVICPISSVPGNLA | -26.87 | Moesta et al. (2002) |
24* | Dsg3 97–111 | FGIFVVDKNTGDINI | -26.58 | Wucherpfennig et al. (1995) |
25@ | Dsg3 810–824 | NDCLLIYDNEGADAT | -24.00 | Moesta et al. (2002) |