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Figure 1 | BMC Bioinformatics

Figure 1

From: Computational promoter analysis of mouse, rat and human antimicrobial peptide-coding genes

Figure 1

Workflow of promoter sequence set preparation and analysis. AMP peptide sequences were collected from ANTIMIC and Genbank databases and searched with TBLASTN against FANTOM3 cDNA sequences applying a cut-off of equal or greater than 60% identity. The promoter regions [-1000, +200 nt] of mouse AMPcg, human and rat orthologs were extracted and submitted to Dragon Motif Builder (DMB) for ab initio motif searching. The resulting consensus motifs were passed to TRANSFAC and compared with known TFBSs using the PATCH program.

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