Skip to main content
Figure 3 | BMC Bioinformatics

Figure 3

From: HMM-ModE – Improved classification using profile hidden Markov models by optimising the discrimination threshold and modifying emission probabilities with negative training sequences

Figure 3

Determination of optimal discrimination threshold. The average MCC(bold black) distribution is overlayed on the sensitivity and specificity plots for each of 10-fold cross validation samples of the PVPK sub-family. Figures are plotted for the default profile HMM-d (top, A), HMM-ModE (center, B) and HMM-Sub(bottom, C).

Back to article page

BMC Bioinformatics

ISSN: 1471-2105

Contact us