Figure 1

Zn-binding site structural motifs derived from the structural alphabet representation of 3 Zn-finger proteins. For each protein, the PDB entry and chain is given, followed below by its amino acid sequence (in capital letters), aligned with the corresponding structural alphabet representation (lower-case letters); 'Z', means a letter cannot be assigned to this residue (see Methods). Zn²⁺-binding residues are underlined and in bold. Only the first 30 amino acid residues are shown. The C_α root-mean-square deviation RMSD of 1LAT and 2NLL from 1HCQ are 1.73 and 1.33 Å, respectively, whereas that of 1LAT from 2NLL is 1.25 Å.