Skip to main content

Table 2 Homologies of selected peptide sequences

From: In silico panning for a non-competitive peptide inhibitor

4thround peptides

Additional round peptides

Synthesized peptides

Rank

Peptide sequence

Docking energy (kcal/mol)

Rank

Peptide sequence

Docking energy (kcal/mol)

Rank

Peptide sequence

Docking energy (kcal/mol)

1

GERD

-115

1

GEKD

-149

1

GEKD

-149

2

SERG

-114

2

SEKD

- 88

2

GERD

-115

3

DSRD

-114

3

GDKD

- 87

3

SERG

-114

4

GDPR

-113

4

DSKD

- 75

38

DDDD

22

5

GDRD

-110

5

GEKE

- 22

   

6

SDRG

-109

      

7

GDRG

-103

      

8

GDGD

-99

      

9

GEDG

-99

      

10

GGGG

-98

      
  1. The homologies of selected peptides ranked in the top 10 after the 4th round of evolution were listed to the left. Additional peptides that contained a lysine (K) residue at the third position were also listed on the middle. The final rank and the synthetic peptide sequences were shown on the right. The DDDD peptide was used as a negative control.