Skip to main content
Figure 2 | BMC Bioinformatics

Figure 2

From: Selective prediction of interaction sites in protein structures with THEMATICS

Figure 2

Comparative ROC Diagram. Comparative ROC diagram for THEMATICS (■), Q-SiteFinder (), and SARIG (▲). True Positive Fraction (true positives predicted/all known positives) is plotted as a function of the False Positive Fraction (false positives predicted/all known negatives), both expressed as percentages, for a test set of 75 proteins. The CatRes/CSA annotations are used to designate the known positive residues and all other residues are taken to be negative. Five data points are shown for THEMATICS, corresponding to Z score cut-off values of 0.95, 0.96, 0.98, 0.99, and 1.00 (with ascending Z score values proceeding from upper right to lower left). The points for THEMATICS are joined by a solid line (—). The three points shown for Q-SiteFinder correspond to the top site only, a combination of the top two sites, and a combination of the top three sites (with ascending number of sites proceeding from lower left to upper right). The points for Q-SiteFinder are joined by a dashed line (- - - -).

Back to article page