Skip to main content

Table 3 THEMATICS success rates for site prediction.

From: Selective prediction of interaction sites in protein structures with THEMATICS

Z Score Cut-Off Correct percentage based on CatRes Partially Correct percentage based on CatRes Total Success based on CatRes Total % Success based on Reference Set 2 Total % Success based on Reference Set 3 Filtration Ratio
1.00 48.5% 29.0% 77.5% 82.2% 89.9% 2.5%
0.99 59.8% 26.0% 85.8% 88.2% 92.9% 3.3%
0.98 66.9% 21.3% 88.2% 90.5% 94.1% 3.8%
  1. Success rate is expressed as correct, partially correct, and total, using a Z score cut-off of 1.00, 0.99 and 0.98 for the test set of 169 enzymes. The total success rate is reported using three different reference sets of active site residues. Reference Set 1 is the CatRes/CSA database only; Reference Set 2 adds annotations from the PDB SITE field and associated journal articles; Reference Set 3 adds residues in contact with bound ligands.