Skip to main content

Table 10 Structural prediction accuracy statistics for the methods benchmarked over 2000 random tRNA selections when scored using an exact match criterion.

From: Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign

   Percent sequence similarity
20–40 40–60 60–80 80–100 0–100
Dynalign new constraint Sens 0.818 0.862 0.923 0.715 0.861
  PPV 0.788 0.832 0.916 0.697 0.834
Dynalign M constraint Sens 0.813 0.854 0.917 0.716 0.855
  PPV 0.781 0.822 0.907 0.698 0.825
FOLDALIGN Sens 0.731 0.846 0.887 0.690 0.835
  PPV 0.815 0.894 0.939 0.846 0.889
StemLoc Sens 0.581 0.894 0.940 0.872 0.860
  PPV 0.747 0.899 0.924 0.876 0.886
Consan Sens 0,786 0.905 0.944 0.769 0.894
  PPV 0.755 0.848 0.873 0.667 0.838
Single Prediction Sens 0.743 0.746 0.774 0.717 0.748
  PPV 0.696 0.688 0.728 0.673 0.693
  1. Results are summarized for sequence similarity values ranging from 20% through 100% in steps of 20% and for the overall data set (0 – 100). Dynalign new constraint refers to Dynalign with probabilistic alignment constraints proposed here. Software version numbers and parameters for the algorithms are described in Section 7.6.