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Table 11 Structural prediction accuracy statistics for the methods benchmarked over 2000 random 5S RNA selections when scored using an exact match criterion.

From: Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign

   Percent sequence similarity
  40–60 60–80 80–100 0–100
Dynalign new constraint Sens 0.850 0.870 0.876 0.869 0.871
  PPV 0.790 0.791 0.782 0.743 0.785
Dynalign M constraint Sens 0.847 0.869 0.876 0.869 0.870
  PPV 0.789 0.789 0.778 0.744 0.782
FOLDALIGN Sens 0.684 0.721 0.772 0.501 0.724
  PPV 0.724 0.750 0.789 0.562 0.752
StemLoc Sens 0.253 0.631 0.858 0.711 0.698
  PPV 0.603 0.751 0.854 0.738 0.786
Consan Sens 0.602 0.743 0.882 0.759 0.786
  PPV 0.598 0.704 0.768 0.608 0.717
Single Prediction Sens 0.655 0.695 0.734 0.744 0.709
  PPV 0.579 0.606 0.641 0.632 0.618
  1. Results are summarized for sequence similarity values ranging from 20% through 100% in steps of 20% and for the overall data set (0 – 100). Dynalign new constraint refers to Dynalign with probabilistic alignment constraints proposed here. Software version numbers and parameters for the algorithms are described in Section 7.6.