Table 2 Average, minimum, maximum sensitivity and specificity over tRNA and 5S RNA alignments in RFAM database for the proposed probabilistic alignment constraint (New constraint) and the previously employed M constraint.
From: Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign
| New constraint | M constraint | ||||
|---|---|---|---|---|---|
| sensitivity | specificity | sensitivity | specificity | ||
| tRNA | avg | 0.999 | 0.827 | 0.997 | 0.816 |
| min | 0.38 | 0.42 | 0.44 | 0.78 | |
| max | 1.00 | 0.99 | 1.00 | 0.85 | |
| 5S RNA | avg | 0.999 | 0.924 | 0.995 | 0.883 |
| min | 0.78 | 0.63 | 0.53 | 0.85 | |
| max | 1.00 | 0.98 | 1.00 | 0.88 | |
