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Table 2 Average, minimum, maximum sensitivity and specificity over tRNA and 5S RNA alignments in RFAM database for the proposed probabilistic alignment constraint (New constraint) and the previously employed M constraint.

From: Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign

  

New constraint

M constraint

sensitivity

specificity

sensitivity

specificity

tRNA

avg

0.999

0.827

0.997

0.816

 

min

0.38

0.42

0.44

0.78

 

max

1.00

0.99

1.00

0.85

5S RNA

avg

0.999

0.924

0.995

0.883

 

min

0.78

0.63

0.53

0.85

 

max

1.00

0.98

1.00

0.88