Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign

BMC Bioinformatics

Table 3 Structural prediction accuracy of Dynalign with the M constraint and the new constraint, and for single sequence prediction over 2000 random tRNA pairs.

Column with '+' refers to Dynalign making use of structural constraints where modified nucleotides that cannot accommodate the canonical A-form helix are forced single-stranded [24].

ISSN: 1471-2105