Skip to main content

Table 3 Structural prediction accuracy of Dynalign with the M constraint and the new constraint, and for single sequence prediction over 2000 random tRNA pairs.

From: Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign

  Dynalign   
New constraint M constraint Single Sequence Prediction
  + - + - + -
Sensitivity 0.926 0.873 0.923 0.866 0.874 0.764
PPV 0.925 0.846 0.922 0.836 0.848 0.707
  1. Column with '+' refers to Dynalign making use of structural constraints where modified nucleotides that cannot accommodate the canonical A-form helix are forced single-stranded [24].