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Table 6 Structural prediction accuracy statistics for the methods benchmarked over 2000 random tRNA selections.

From: Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign

   Percent sequence similarity
20–40 40–60 60–80 80–100 0–100
Dynalign new constraint Sens 0.830 0.874 0.936 0.719 0.873
  PPV 0.800 0.845 0.930 0.701 0.846
Dynalign M constraint Sens 0.824 0.867 0.930 0.719 0.866
  PPV 0.792 0.834 0.921 0.701 0.836
FOLDALIGN Sens 0.753 0.858 0.898 0.690 0.848
  PPV 0.838 0.906 0.949 0.846 0.902
StemLoc Sens 0.587 0.896 0.943 0.871 0.862
  PPV 0.755 0.901 0.926 0.876 0.889
Consan Sens 0.800 0.909 0.945 0.768 0.899
  PPV 0.769 0.852 0.873 0.667 0.843
Single Prediction Sens 0.757 0.762 0.785 0.717 0.764
  PPV 0.709 0.703 0.738 0.673 0.707
  1. Results are summarized for sequence similarity values ranging from 20% through 100% in steps of 20% and for the overall data set (0 – 100). Dynalign new constraint refers to Dynalign with probabilistic alignment constraints proposed here. Software version numbers and parameters for the algorithms are described in Section 7.6.