Skip to main content

Table 6 Structural prediction accuracy statistics for the methods benchmarked over 2000 random tRNA selections.

From: Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign

  

Percent sequence similarity

20–40

40–60

60–80

80–100

0–100

Dynalign new constraint

Sens

0.830

0.874

0.936

0.719

0.873

 

PPV

0.800

0.845

0.930

0.701

0.846

Dynalign M constraint

Sens

0.824

0.867

0.930

0.719

0.866

 

PPV

0.792

0.834

0.921

0.701

0.836

FOLDALIGN

Sens

0.753

0.858

0.898

0.690

0.848

 

PPV

0.838

0.906

0.949

0.846

0.902

StemLoc

Sens

0.587

0.896

0.943

0.871

0.862

 

PPV

0.755

0.901

0.926

0.876

0.889

Consan

Sens

0.800

0.909

0.945

0.768

0.899

 

PPV

0.769

0.852

0.873

0.667

0.843

Single Prediction

Sens

0.757

0.762

0.785

0.717

0.764

 

PPV

0.709

0.703

0.738

0.673

0.707

  1. Results are summarized for sequence similarity values ranging from 20% through 100% in steps of 20% and for the overall data set (0 – 100). Dynalign new constraint refers to Dynalign with probabilistic alignment constraints proposed here. Software version numbers and parameters for the algorithms are described in Section 7.6.