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Table 7 Structural prediction accuracy statistics for the methods benchmarked over 2000 random 5S RNA selections.

From: Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign

   Percent sequence similarity
20–40 40–60 60–80 80–100 0–100
Dynalign new constraint Sens 0.895 0.903 0.914 0.909 0.907
  PPV 0.838 0.824 0.821 0.785 0.821
Dynalign M constraint Sens 0.892 0.901 0.912 0.909 0.905
  PPV 0.837 0.821 0.815 0.786 0.817
FOLDALIGN Sens 0.726 0.753 0.787 0.510 0.749
  PPV 0.772 0.784 0.803 0.572 0.778
StemLoc Sens 0.272 0.673 0.899 0.776 0.740
  PPV 0.652 0.805 0.901 0.826 0.840
Consan Sens 0.666 0.799 0.931 0.865 0.842
  PPV 0.671 0.761 0.817 0.722 0.775
Single Prediction Sens 0.680 0.722 0.766 0.784 0.739
  PPV 0.603 0.632 0.672 0.673 0.647
  1. Results are summarized for sequence similarity values ranging from 20% through 100% in steps of 20% and for the overall data set (0 – 100). Dynalign new constraint refers to Dynalign with probabilistic alignment constraints proposed here. Software version numbers and parameters for the algorithms are described in Section 7.6.