Skip to main content

Table 7 Structural prediction accuracy statistics for the methods benchmarked over 2000 random 5S RNA selections.

From: Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign

  

Percent sequence similarity

20–40

40–60

60–80

80–100

0–100

Dynalign new constraint

Sens

0.895

0.903

0.914

0.909

0.907

 

PPV

0.838

0.824

0.821

0.785

0.821

Dynalign M constraint

Sens

0.892

0.901

0.912

0.909

0.905

 

PPV

0.837

0.821

0.815

0.786

0.817

FOLDALIGN

Sens

0.726

0.753

0.787

0.510

0.749

 

PPV

0.772

0.784

0.803

0.572

0.778

StemLoc

Sens

0.272

0.673

0.899

0.776

0.740

 

PPV

0.652

0.805

0.901

0.826

0.840

Consan

Sens

0.666

0.799

0.931

0.865

0.842

 

PPV

0.671

0.761

0.817

0.722

0.775

Single Prediction

Sens

0.680

0.722

0.766

0.784

0.739

 

PPV

0.603

0.632

0.672

0.673

0.647

  1. Results are summarized for sequence similarity values ranging from 20% through 100% in steps of 20% and for the overall data set (0 – 100). Dynalign new constraint refers to Dynalign with probabilistic alignment constraints proposed here. Software version numbers and parameters for the algorithms are described in Section 7.6.