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Table 1 Number of periodic genes detected using different methods for simulated data

From: Spectral estimation in unevenly sampled space of periodically expressed microarray time series data

Noise levels (σ) Missing ratio P
Lomb-Scargle method Our Algorithm
0.01 15% 93 98
  20% 88 92
  40% 68 80
  65% 40 65
0.2 15% 85 92
  20% 75 85
  40% 60 78
  65% 32 50
0.6 15% 72 89
  20% 65 80
  40% 51 65
  65% 28 47
  1. The simulated data consists of 1000 time series (genes). The total number of periodic genes is 100. P is the number of periodic genes that are statistically significant for a FDR level of q = 0.02. The number of false positives FP can be computed as FP = q*TP/(1-q), where TP is the number of true positives. Keeping q at a fixed level ensures that we do not sacrifice specificity for sensitivity.