The ADAPT tool. The ADAPT tool shows positions of probes within the most highly differentially expressed up-regulated gene and the most highly differentially expressed down-regulated gene by fold change. The ADAPT tool used with RefSeq database confirms BLASTN results (Table 1) that probes 1,3, and 11 for gene Hsbp1 do not have perfect sequence matches with the gene. The diagram also elucidates the extent of probe overlap between probes 5 through 10 for Hsbp1 (A). The ADAPT used with the Ensemble database for Hsbp1 gives different results than the ADAPT tool used with the RefSeq database, however the results still show that probe 11 does not have a perfect sequence match with the gene (B). For gene Id2, the ADAPT tool shows that all probes have perfect sequence matches with the gene whether using RefSeq or Ensemble databases (C and D).