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Figure 5 | BMC Bioinformatics

Figure 5

From: AYUMS: an algorithm for completely automatic quantitation based on LC-MS/MS proteome data and its application to the analysis of signal transduction

Figure 5

Comparison of the results obtained using AYUMS versus manual operation. The output performance of AYUMS and manual operation is compared based on the time-series proteome data of A431 cells stimulated with EGF. The observation points are 0 min, 1 min, and 5 min. The proteins with the top six Mascot scores were selected for the comparison. (a) 2D-Plot data of the output obtained by manual operation (x-axis: time, y-axis: fold activation of each protein). (b) 2D-Plot data of the output obtained by AYUMS. (c) The correlation chart of 38 phosphorylated proteins for 1-min and 5-min observation points between AYUMS and manual operation. The correlation coefficient was 0.890.

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BMC Bioinformatics

ISSN: 1471-2105

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