Figure 2
From: Multivariate Analysis and Visualization of Splicing Correlations in Single-Gene Transcriptomes
Two metric indices introduced in this work. A, The Linkage Vector, D, compares splicing correlation between two loci in two populations; B, The Linkage Change Index S D measures displacement of D from the zero-change axis (x'). C, S D is a sinusoidal function of the phase φ between D and x', the axis of zero linkage change. Positive values indicate an increasing positive or decreasing negative linkage change, and magnitude |S D | > 1 indicates a sign reversal (c.f. panel B). D, The Accuracy Index, = a/b, measures displacement of a point estimator x0 from the center of mass of a distribution p(x).