Table 5 Hinge frequency of occurrence vs. conservation bin.
From: Hinge Atlas: relating protein sequence to sites of structural flexibility
| Â | Active site residue propensity | Hinge residue propensity | ||||||
|---|---|---|---|---|---|---|---|---|
| Â | Enzymes in Hinge Atlas | Hinge Atlas | Enzymes in Hinge Atlas | |||||
Conservation score bin | Active site residues | HI | p-value | Hinge residues | HI | p-value | Hl | p-value |
Top 1/5th | 813 | 0.63 | <10-29 | 157 | -0.045 | 0.057 | -.0093 | .45 |
2nd 1/5th | 53 | -0.55 | <10-29 | 162 | -0.031 | 0.13 | -.027 | .30 |
3rd 1/5th | 44 | -0.63 | <10-29 | 161 | -0.034 | 0.11 | -.015 | .40 |
4th 1/5th | 22 | -0.94 | <10-29 | 176 | 0.0050 | 0.44 | -.086 | .043 |
Bottom 1/5th | 15 | -1.1 | <10-29 | 213 | 0.090 | 0.00061 | .113 | .0029 |
| Â | 947 | Â | Â | 869 | Â | Â | Â | Â |