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Table 2 Description of the dataset.

From: Discovering functional linkages and uncharacterized cellular pathways using phylogenetic profile comparisons: a comprehensive assessment

  Number of Proteins (in KEGG) Number of possible functional linkages examined Number of positives
Pathways E. coli Yeast E. coli Yeast E. coli Yeast
All Pathways 1,347 1,191 708,645 635,628 43,968 35,674
Carbohydrate metabolism 292 241 33,153 26,565 5,450 4,859
Energy metabolism 135 134 8,128 8,001 2,113 3,060
Lipid metabolism 83 100 2,080 4,656 602 1,232
Nucleotide metabolism 108 113 5,050 5,995 3,686 5,082
Amino acid metabolism 237 216 20,100 19,900 3,328 3,620
Metabolism of cofactors and vitamins 146 113 7,875 5,253 1,085 740
Translation 80 185 3,081 15,400 1,761 10,792
Membrane transport 259   24,531   16,834  
Folding, sorting, and degradation   82   2,926   809