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Table 2 Rate constants versus network stiffness in system (A1).

From: A hybrid multiscale Monte Carlo algorithm (HyMSMC) to cope with disparity in time scales and species populations in intracellular networks

Network Stiffness ~O(k1/k2) Slow Network k2 = k-2(s-1)
102 1.0
103 10-1
104 10-2
105 10-3
106 10-4
  1. k1 = k-1 = 100 s-1 and XA(t = 0) = XB(t = 0) = XC(t = 0) = 500 are used in all 5 cases.