Table 2 Enrichment of cell cycle genes. The proportions of genes that belong to the 793 cell cycle genes identified by Spellman et al. [7] are calculated for B⁺R⁺ and B⁺R^-. We then test whether the enrichment of the known cell cycle genes in B⁺R⁺ is statistically higher than that in B⁺R^-. The cumulative hypergeometric distribution is used to determine the statistical significance (see the Appendix for details). In most cases (7/9), except for Abf1 and Ace2, the known cell cycle genes are more enriched in B⁺R⁺ than in B⁺R^-.

Abf1

19/144

6/103

0.0439

(144,19,103,6)

Ace2

14/44

7/37

0.1433

(44,14,37,7)

Cin5

24/69

11/73

0.0055

(69,24,73,11)

Fkh1

41/96

3/37

5.9970e-005

(96,41,37,3)

Fkh2

54/90

0/26

3.7043e-009

(90,54,26,0)

Rap1

13/82

2/65

0.0092

(82,13,65,2)

Swi4

60/84

15/62

1.2199e-008

(84,60,62,15)

Swi5

22/42

14/64

0.0012

(42,22,64,14)

Swi6

37/49

42/95

2.7593e-004

(49,37,95,42)